Studies on Antibiotics and Related Substances. X. Syntheses of Some Unsaturated Ketocarboxylic Acids, Anti-tumor Substances

Thermodynamic Properties of Solutions of Amino Acids and Related Substances

The effect of temperature on the thermodynamic ionization constants of compounds with dipole moments greater than those of the a-amino acids has not heretofore been studied. In this paper results are given for glycylglycine and c-aminocaproic acid, two substances with similar dipole moments. Measurements are also included for aspartic acid, which has recently been studied at 25” in cells withou...

On Tumor-Producing Chemical Substances*

The following is a review of the studies carried out in this laboratory during the past seven or eight years with the view of (a) elucidating the effect of certain exogenous tumor-producing chemical agents and (b) ascertaining the presence within the human body of chemical substances that may call forth the formation of tumors. The present review is based in the main on the results obtained by ...

The Lipotropic Action of Some Sulfur-con- Taining Amino Acids and Related Substances

Studies in the Physical Chemistry of Amino Acids, Peptides, and Related Substances

1. As an introduction to the relations that obtain in biochemical systems containing several components, some ionic, some dipolar ionic, the solubility of cystine has been investigated in the presence of glycine and neutral salts. 2. Both glycine and sodium chloride increase cystine solubility at all concentrations. The interaction between cystine and ions is, however, diminished with increase ...

Effects of some growth substances on mitosis.

Radiomimetic action of growth substances, also called hormones, has been demonstrated by several workers Some of the growth substances are used as growth promotors while others are used as herbicides for weed control. As they prove toxic beyond certain concentrations, it is fruitful to study their effects at different concentrations. This paper describes the results of an experiment involving d...